Our application, ABK’s PubMed Search String Generator, is an indispensable tool for researchers looking to streamline their literature review process, particularly when using PubMed. This application simplifies the generation of advanced search strings by expertly handling Population, Intervention, Comparator(s), and Outcome(s) (PICO) terms. By leveraging the power of the MeSH database, the application performs a detailed search word analysis to create precise PubMed queries. It allows users to easily enter search keywords, and with a single click, generates a fully-optimized search string, tailored specifically to their research needs. The generated PubMed search string can be effortlessly copied to the clipboard, enabling quick transfer to the PubMed search box for immediate results. To further refine search outcomes, users can take advantage of PubMed’s filter options. Beyond search string generation, the application supports comprehensive research management. Users can review their PubMed search history to refine their strategies and ensure they are accessing the most relevant articles. The application also provides tools to cite articles efficiently, offering features like an APA builder and a free citation builder for seamless referencing. Whether you are conducting systematic reviews, meta-analyses, or any research requiring precise literature searches, our application provides the advanced tools and support you need to succeed. From generating accurate search terms to ensuring proper citation in your work, this tool is designed to enhance your research efficiency and accuracy.